Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. 2010;24(10):1423-32. doi:10.1002/ptr.3207, Salmi HA, Sarna S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. As the liver can purify our blood, the effect will be felt in our skin. While milk thistle has not shown any side effects in scientific tests, if you are pregnant or lactating, please consult your health care provider before taking milk thistle. Milk thistle can be taken in the form of an oral supplement or in tea. Might Cause Abdominal Issues 2. The typical dose is 200 to 420 mg daily taken thice daily with meals for 2 months, then 280 mg/day in three divided doses. Milk thistle tonic is typically made by steeping a tablespoon of crushed seed in three cups of hot water for 20 minutes. Though it’s harder to control the dose this way, it is safe; all parts of the plant are edible and have been used as a regular part of people’s diets for centuries. Effect of silymarin on chemical, functional, and morphological alterations of the liver. In fact, a survey funded by the National Institutes of Health reported that 23 percent of 1,145 people with hepatitis C used herbal supplements, with milk thistle being by far the most common.. There are no known side effects or contraindications. Side effects. Can Cause Weakness The therapeutic potential of milk thistle in diabetes. While it is not without benefit, milk thistle doesn't appear to exert a significant effect on either liver tissues or liver function.. However, side effects … Itchiness 3. Research on the effects of milk thistle in people with hepatitis is not consistent. 2008;47(2):605-12. Phytomedicine. Dietary supplements containing milk thistle are sold in natural foods stores, drugstores, and stores specializing in herbal products. Speak to your doctor … At present, there is not enough scientific data to say whether milk thistle can help the liver or not. 2012 Jul 18;308(3):274-82. A 2012 study published in the Journal of the American Medical Association (JAMA) confirmed this. Scand J Gastroenterol. Effects of Silybum marianum (L.) Gaertn. Thank you, {{form.email}}, for signing up. In some cases the user may suffer from stomach discomfort, whether or not in combination with diarrhea. People with allergies to ragweed, daisies, artichokes, kiwi, or plants in the aster family may also be allergic to milk thistle. If this occurs, it is wise to stop … Can Ivy Gourd Treat Diabetes and High Cholesterol? 2014;11(2):167-74. doi:10.1900/RDS.2014.11.167. Blessed thistle is considered safe when used as a tea. Despite the positive findings, subsequent studies have been unable to replicate the results or demonstrate that milk thistle prescribed on its own would render the same effects. Blessed thistle should be avoided in people with inflammatory bowel diseases like Crohn's disease and ulcerative colitis. Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. By contrast, fungal contamination is rare in milk thistle tea bags, extracts, capsules, tablets, and soft gels. The most common side effect of taking milk thistle is mild gastrointestinal upset. People who are allergic to ragweed should also avoid consuming milk thistle tea. Milk thistle (Silybum marianum) is a perennial herb believed to have medicinal properties. Today, even scientists agree that milk thistle has unique anti-inflammatory properties that can help to flush out toxins from the liver. Can Have Interactions During Breastfeeding And Pregnancy 7. Milk thistle has few known side effects, but can cause allergic reaction in some people. Milk thistle is also known by the names Saint Mary's thistle, variegated thistle, and Scotch thistle. Milk thistle tea may cause allergic reaction in people who are allergic to the milk thistle plant and other daisy plants. Women that are pregnant or nursing should be advised not to drink this tea. Milk thistle is commonly used as a home remedy to treat liver problems, often under the presumption that it will "detoxify" the liver. The most common side effects aren’t serious and include gastrointestinal upset, … A 2016 … 1982;17(4):517-21. doi:10.3109/00365528209182242, Seeff LB, Curto TM, Szabo G, et al. Milk Thistle. There are no guidelines directing the appropriate use of milk thistle. 2016;2016:5147468. If left untreated, anaphylaxis can lead to shock, coma, cardiac or respiratory failure, or death. The same applies to blessed thistle supplements and tinctures. You can harvest these and extract the seeds by removing the fluffy fibers surrounding them. Milk thistle is a flowering plant that was named due to the milk like substance that is produced in the stem and leaves of the plant. Few of these claims are supported by hard evidence. It is possible to … Ⓒ 2020 About, Inc. (Dotdash) — All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Milk thistle and dandelion is a popular combination for people who seek to promote liver function. Nonsteroidal anti-inflammatory drugs (NSAIDs) like Advil (ibuprofen), Celebrex (celecoxib), and Voltaren (diclofenac), Statin drugs like Mevacor (lovastatin) and Lescol (fluvastatin). Other galactagogic ingredients found in mother’s milk Tea include blessed thistle, coriander, and fenugreek. 1. 2015;22(2):290-6. doi:10.1016/j.phymed.2014.12.010, Kazazis CE, Evangelopoulos AA, Kollas A, Vallianou NG. You can then either air-dry the seeds or use a home dehydrator (which reduces the risk of fungal contamination). Drug Interactions: Milk thistle tea has many active ingredients that can interact with drugs for everything from diabetes and hypertension to sleep aids and liver disease. 2015 Feb 15;22(2):290-6. Despite being well-tolerated in the study participants, silymarin (prescribed thrice-daily in 420- or 700-milligram doses) had no tangible effect on liver enzymes. May Cause Allergic Reactions 3. Milk thistle is also used to treat serpent bites and mushroom poisoning. Get emergency medical help if you have any of these signs of an allergic reaction while taking milk thistle: hives; difficult breathing; swelling of your face, lips, tongue, or throat. If you're allergic to any of these ingredients, it can have serious … Phytomedicine. 4 Simple Fatty Liver Prevention Solutions You Should Know, 3 Natural Ways You Can Reduce the Side Effects of Your Antibiotics, Milk thistle in liver diseases: past, present, future, Effect of silymarin on chemical, functional, and morphological alterations of the liver. Milk thistle seems to have few side effects, even when taken for several years. So any effects you noticed probably weren’t due to the milk thistle. DOI: 10.1111/j.1572-0241.2005.00262.x. Milk thistle is sometimes used by people with chronic hepatitis C (a viral infection characterized by the progressive scarring of the liver). Rambaldi, A.; Jacobs, B.; Iaquinto G, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. 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